Invited Plenary Speakers

G. Michael Blackburn (University of Sheffield, England) Phosphate  Stability and Transferability – the Paradox of Life

Marvin H. Caruthers (University of Colorado, Boulder, CO) Oligonucleotide Synthesis Interfaced with Molecular Biology and Nanotechnology

Jyoti Chattopadhyaya (University of Uppsala, Uppsala, Sweden) Carba-LNA Modified DNA Can Control the Phosphate degradation of the Complementary Target mRNA Strand by harnessing the Relative Hydration in the Hybrid Duplex

Wlodzimierz J. Krzyzosiak (Institute of Bioorganic Chemistry, Polish Academy of Sciences, Poznan, Poland)  RNA interference targeting CAG repeats in Huntington’s disease

Janez Plavec (Slovenian NMR Center, Ljubljana, Slovenia) High-resolution NMR structure of a DNA quadruplex containing ALS and FTD related GGGGCC repeat                    

Naoki Sugimoto (FIBER and Konan University, Kobe, Japan) Quadruplexes as New Targets of Nucleic Acid Drugs

Kazunari Taira (Tokyo University and Graduate School of Social Welfare, Tokyo, Japan) Revisit of the most stable monosaccharide “Glucose” and the most stable disaccharide “Trehalose”

Zhen Xi (Nankai University, Tianjin, China) Nucleic acid nanoparticle construction by PCR using flexible branched primers

Xianbin Yang (AM Biotechnologies, Houston, TX) Phosphate backbone-modified RNA: not an easy path to pursue

Li-he Zhang (Peking University, Beijing, China) Study on Isonucleoside (isoNA) incorporation around cleavage site of passenger strand of siRNA and in loop region of thrombin binding aptamers

Gerald Zon (TriLink BioTechnologies, San Diego, CA) Hot Start PCR: Design and Applications of Thermo-Sensitive Oligonucleotide Primers and dNTPs for Improved PCR Performance