Symposium Program
Thursday, October 15, 2015 Lecture Hall - IFE, LUT, Zwirki 36, Lodz
8.30 - 9.00 Registration and poster adjustment
9.00 - 9.15 Barbara Nawrot - Introduction
Chairperson of the session - Piet Herdewijn
9.15 - 9.45 G. Michael Blackburn (University of Sheffield, England) Phosphate Stability and
Transferability - the Paradox of Life
9.45 - 10.15 Marvin H. Caruthers (University of Colorado, Boulder, CO) Oligonucleotide
Synthesis Interfaced with Molecular Biology and Nanotechnology
10.15 - 10.45 Xianbin Yang (AM Biotechnologies, Houston, TX) Phosphate backbone-modified RNA:
not an easy path to pursue
10.45 - 11.15 Jyoti Chattopadhyaya (University of Uppsala, Uppsala, Sweden) Carba-LNA Modified
DNA Can Control the Phosphate degradation of the Complementary Target mRNA
Strand by harnessing the Relative Hydration in the Hybrid Duplex
11.15 - 12.00 Coffee break, sparkling wine and wishes
Chairperson of the session - Maria Koziołkiewicz
12.00 - 12.30 Wlodzimierz J. Krzyzosiak (IBC, Polish Academy of Sciences, Poznan, Poland)
RNA interference targeting CAG repeats in Huntington's disease
12.30 - 13.00 Li-he Zhang (Peking University, Beijing, China) Study on Isonucleoside (isoNA)
incorporation around cleavage site of passenger strand of siRNA and in loop region of
thrombin binding aptamers
13.00 - 13.30 Kazunari Taira (Tokyo University and Graduate School of Social Welfare, Tokyo, Japan)
Revisit of the most stable monosaccharide “Glucose” and the most stable disaccharide
“Trehalose”
13.30 -14.15 Lunch break
14.15 - 15.15 Poster session
Chairperson of the session - Ryszard Adamiak
15.15 - 15.45 Naoki Sugimoto (FIBER and Konan University, Kobe, Japan) Quadruplexes as New
Targets of Nucleic Acid Drugs
15.45 - 16.15 Janez Plavec (Slovenian NMR Center, Ljubljana, Slovenia) High-resolution NMR
structure of a DNA quadruplex containing ALS and FTD related GGGGCC repeat
16.15 - 16.45 Zhen Xi (Nankai University, Tianjin, China) Nucleic acid nanoparticle construction by
PCR using flexible branched primers
16.45 - 17.15 Gerald Zon (TriLink BioTechnologies, San Diego, CA) Hot Start PCR: Design and
Applications of Thermo-Sensitive Oligonucleotide Primers and dNTPs for Improved PCR
Performance
17.15 - 17.35 Wojciech J. Stec; ACNOWLEDGMENTS
17.35 Closing the Symposium
Friday, October 16, 2015, CMMS PAS. Sienkiewicza 112, Lodz
Post-Symposium: Presentation of the Department of Bioorganic Chemistry
9.20 - 9.30 Barbara Nawrot - Department Introduction
9.30 - 10.00 Piotr Guga (Laboratory of Synthesis of Oligonucleotides and Their Analogues)
10.00 - 10.15 Katarzyna Jastrzebska (Laboratory of Synthesis of Oligonucleotides and Their Analogues)
10.15 - 10.45 Arkadiusz Chworos (Laboratory of Biomaterials)
10.45 - 11.00 Dominika Jedrzejczyk (Laboratory of Biomaterials)
11.00 - 11.30 Coffee break
11.30 - 12.00 Marcus Duchler (Laboratory of Molecular Medicine)
12.00 - 12.15 Liliana Czernek (Laboratory of Molecular Medicine)
12.15 - 12.45 Barbara Nawrot (Laboratory of Therapeutic Oligonucleotides)
12.45 - 13.00 Anna Chwialkowska (Laboratory of Therapeutic Oligonucleotides)
13.00 - 13.15 Marcin Cieslak (Screening Laboratory)
13.15 - 14.15 Lunch
14.30 Lodz sightseeing for the invited speakers
